Guselkumab improved joint swelling, spinal pain, skin symptoms, and overall disease activity in a substantial number of patients with psoriatic arthritis through 2 years.
Guselkumab shows early and durable improvement in joint symptoms, spinal pain, and skin clearance through 2 years in biologic-naive patients with active psoriatic arthritis , with a considerable proportion of patients achieving treatment targets.
Adverse events assessed through week 112 included the occurrence of IBD and uveitis or their exacerbation in patients with prior IBD or uveitis.By week 100, peripheral arthritis improved with a 69%-88% reduction in mean swollen and tender joint counts, skin psoriasis symptoms improved by 72%-96%, and spinal pain improved by 46%-50% across both guselkumab regimens.
Arthropathic Psoriasis Psoriatic Arthropathy Psa Arthritis Joint Inflammation Uveitis Psoriasis Prostate Specific Antigen PSA PSA - Prostate Specific Antigen Pain Inflammatory Bowel Disease IBD - Inflammatory Bowel Disease IBD Prostate Carcinoma Malignant Prostate Neoplasm Prostate Cancer Cancer Of The Prostate Pain Management Psoriatic Nail Disease
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