Research published in Virology Journal reports that coinfection of SARS-CoV-2 and human herpesvirus infection is not associated with poor outcomes.
Kendall's Tau-b Correlation was used to determine the correlation between the COVID-19 load viral with the herpesvirus load viral to determine the association of the variables corticosteroid use, lymphocytopenia, outcomes, and neurological symptoms with herpesvirus detection, Pearson's Chi-square or Fisher's exact tests were used, and the viral load was evaluated using the Mann–Whitney test . Among the patients, 39.6% were considered to have severe disease , and 58.
With respect to the prevalence of herpesviruses, 79.2% of the patients tested positive for at least one herpesvirus. Of the 42 patients, 75.0% showed coinfection with two or more viral subtypes. The most prevalent herpes viruses were HHV-6 , CMV , HHV-7 , and HHV-8 . The HSV-1 load correlated with the SARS CoV-2 load . The other correlations were weak and without statistical association, with positive tests for CMV, HHV-7 and HHV-8 and negative tests for EBV and HHV-6 .
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