Houston Methodist researchers will be part of a national consortium funded by an up to $49 million award from the U.S.
Houston MethodistOct 3 2024 Government's Advanced Research Projects Agency for Health to develop a vaccine against two of the most common and destructive strains of herpesviruses that latently infect a majority of Americans and can lead to acute infections, multiple forms of cancer, autoimmune disease and birth defects .
Epstein-Barr causes significant disease in adolescents and young adults as the cause of mono and also can later cause lymphomas, gastric and nasopharyngeal cancer, multiple sclerosis and diseases like non-Hodgkin's lymphoma and certain leukemias in transplant patients.
A critical and innovative aspect to our strategy is the targeting of antigens essential to distinct stages of viral infection – beyond initial entry – to also include cell-to-cell spread, immune evasion and the reactivation stages linked to cancer, autoimmune disease and other complications."
Antibody Antibody Discovery Antigen Autoimmune Disease Birth Defects Cancer Cell Cytomegalovirus Efficacy Laboratory Ph Protein Protein Engineering Research RNA Synthetic Biology Therapeutics
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