How do you like to unwind at night, before switching off the bedroom lamp and going to sleep? A couple of chapters of a thrilling novel perhaps? Maybe a spot of meditation?
Until five weeks ago my relaxation method of choice was to scroll mindlessly through Instagram looking at pictures of food.
The extraordinary boom in the popularity of weight-loss injections has meant that, suddenly, we've had to learn a whole new language. The revelation for those of us taking drugs like Ozempic is that as well as decreasing appetite, it either hugely reduces 'food noise' or silences it altogether. Last Saturday I watched while eating raw carrot and homemade tzatziki. I haven't had an alcoholic drink since I started injecting and the very thought of booze or anything sugary makes me feel queasy.
She adds: There are people who can't work because they are unable to focus. Intense food noise can also interfere with and ruin personal relationships because the person can't be present in the moment. It can destroy social lives because the noise makes it hard to function or think straight. He says: 'Food noise is a manifestation of appetite and appetite is rather complex. I like to conceptualise it as a triangle.
'But if you're really full, then the food will need to have a seriously high reward element for you to want it, and that's going to be something sugary or fatty. This is a phenomenon known as the 'dessert stomach'.' 'I'm going to Montreal soon and I've already been online researching all the restaurants near my hotel and looking at their menus and reviews. That's food noise.
Of those questioned, 67 per cent of obese participants said they wished they didn't think about food as often as they did, compared to 48 per cent of those who fell into a healthy weight range. But GLP-1 doesn't just communicate with the gut. When released after eating, it also latches onto the vagus nerve, which sends a signal to our brain that we are full and means we stop thinking about food. Ozempic and similar drugs are believed to work longer in the brain, too. 'In other words, the drug reduces the chance of food noise percolating up into your executive consciousness,' says Professor Yeo.
'The scanner allows us to see whether the reward part of their brain lights up more or less under certain circumstances. And what we've found is that many obese people will have the brain of a hungry person even though they have just eaten.' 'Ozempic changes one hormone in the body, Mounjaro changes two – and that can lead to incredible outcomes, so what that tells us is that, for people with obesity, it's a hormonal deficiency that needs to be fixed.'
'People will often have ruminations about what they've eaten,' says Dr Silver. 'Those thoughts will be telling them that they've eaten too much, they're greedy, a pig and have ruined a diet . . . and on and on it goes.'
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