The nationwide study from Denmark, published in the British Medical Journal, appears to contradict some earlier studies that suggested HRT protects against cognitive decline if treatments are started near the onset of menopause
But in this new study, the link between HRT use and dementia persisted regardless of when treatment started.
"The observed associations could be artefactual and should not be used to infer a causal relationship between hormone therapy and dementia risk" or to help doctors and patients make decisions about using HRT, the authors of the study said. Study leader Dr Amani Meaidi of the Danish Cancer Society Research Center in Copenhagen said while the study cannot prove HRT contributes to dementia, causality"is biologically plausible," and further research is needed.
If lifestyle changes do not help and there are no medical reasons to avoid HRT, doctors are advised to prescribe hormone therapy with the shortest duration and the smallest dose possible, she said. The Menopause Charity says body-identical HRT has already been shown to help reduce the long-term risk for women of osteoporosis, heart disease, and even colon cancer., which may be using cookies and other technologies. To show you this content, we need your permission to use cookies. You can use the buttons below to amend your preferences to enablecookies or to allow those cookies just once.
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