Humans, and piglets, and bears, oh my! Preventing dangerousbloodclots unirdg_news sciencemagazine
when they are still for days, weeks, months, or even years at a time. The study is published today , inIf you've ever taken a long haul flight, you might have taken advice to prevent a dangerous blood clot—deep vein thrombosis—from forming in one or both of your legs, while you sit still for multiple hours, dreaming of your destination. Perhaps you set a reminder to get up and walk around, and you wore compression socks to keep the blood from pooling in your legs.
The discovery that a protein known as Hsp47 is dramatically reduced—by 55 times—when someone is immobilized for a much longer period than a flight, could lead toto help those who have inherited blood clotting disorders that put them at risk for pulmonary embolism, heart attack, and stroke. Professor Jon Gibbins led the work at the University of Reading. He said,"It seems counterintuitive that people who have severe paralysis don't appear to be at higher risk of blood clots. This tells us that something interesting is happening. And it turns out that reducing levels of Hsp47 plays a key role in preventing clots, not just in humans, but in other mammals, including bears and pigs.
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