Brian Murphy has motor neurone disease and is stuck in hospital waiting for a care package.
BBC Scotland health producer
The critical care wards at the Queen Elizabeth University Hospital in Glasgow are the busiest in Scotland and have been full since the pandemic began. "I may only have months to live and every day I'm here is a day I'm not at home with my family," Brian said.The 50-year-old has motor neurone disease, a condition that progressively damages parts of the nervous system.
"It's almost a deprivation of liberty being stuck in hospital when you could and should be at home," said Brian, a former cardiologist.
United Kingdom Latest News, United Kingdom Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Succession premiere interrupted by Brian Cox screaming on red carpetAn interview with Fisher Stevens on the red carpet at the Succession premiere was interrupted on Monday as actor Brian Cox could be heard bellowing in the background
Read more »
Mum who lost remarkable 14st left with 'body of 90-year-old' due to loose skinKristina Murphy managed to shift more than half her body weight but has been left feeling 'crushed' by the 25lbs of loose skin around her stomach.
Read more »
Mark Harmon and Pauley Perrette to return to NCIS? Here's what their co-star teasedNCIS star Brian Dietzen teased a future plot line featuring former co-stars Mark Harmon, Pauley Perrette, and Michael Weatherly
Read more »
Neuro-Immune Modulation of Cholinergic Signaling in an Addiction Vulnerability TraitSign-tracking (ST) describes the propensity to approach and contact a Pavlovian reward cue. By contrast, goal-trackers (GTs) respond to such a cue by retrieving the reward. These behaviors index the presence of opponent cognitive-motivational traits, with STs exhibiting attentional control deficits, behavior dominated by incentive motivational processes, and vulnerability for addictive drug taking. Attentional control deficits in STs were previously attributed to attenuated cholinergic signaling, resulting from deficient translocation of intracellular choline transporters (CHTs) into synaptosomal plasma membrane. Here, we investigated a posttranslational modification of CHTs, poly-ubiquitination, and tested the hypothesis that elevated cytokine signaling in STs contributes to CHT modification. We demonstrated that intracellular CHTs, but not plasma membrane CHTs, are highly ubiquitinated in male and female sign-tracking rats when compared with GTs. Moreover, levels of cytokines measured in cortex and striatum, but not spleen, were higher in STs than in GTs. Activation of the innate immune system by systemic administration of the bacterial endotoxin lipopolysaccharide (LPS) elevated ubiquitinated CHT levels in cortex and striatum of GTs only, suggesting ceiling effects in STs. In spleen, LPS increased levels of most cytokines in both phenotypes. In cortex, LPS particularly robustly increased levels of the chemokines CCL2 and CXCL10. Phenotype-specific increases were restricted to GTs, again suggesting ceiling effects in STs. These results indicate that interactions between elevated brain immune modulator signaling and CHT regulation are essential components of the neuronal underpinnings of the addiction vulnerability trait indexed by sign-tracking.
Read more »