Multiple sclerosis (MS) is a chronic inflammatory disease in which the immune system attacks the central nervous system.
Ludwig-Maximilians-Universitaet Muenchen Oct 4 2024 Multiple sclerosis is a chronic inflammatory disease in which the immune system attacks the central nervous system . This impairs the transmission of signals between the brain and body and can lead to deficits in vision, motor control, sensation, and cognitive impairment. The causes of MS are still incompletely understood. In a study of identical twins, a team led by PD Dr.
The twin cohort allows the analysis of high-risk patients Genes and the environment partially determine who might get MS. Monozygotic twins offer a unique insight into this, as these factors are largely identical. As the healthy twin has an elevated risk of also developing MS, they allow researchers to investigate the early stages of MS. "It's a unique opportunity to investigate high-risk patients before the disease manifests," says Vladyslav Kavaka, first author of the paper.
These properties show that these CD8 T cells are migratory in the blood and are already embarking on their journey to the central nervous system, where we encounter the same cells." The researchers also found this cell type in the brain tissue of MS patients, which indicates lasting changes in the CNS.
Multiple Sclerosis Sclerosis Blood Brain Cell Central Nervous System Chronic Diagnostic Inflammation Inflammatory Disease Nervous System Twins
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