Researchers discovered liver resident macrophages' pivotal role in defending against gut bacteria and related substances entering via the portal vein, particularly under compromised intestinal barrier conditions. Identified as 'sentinel macrophages,' they are activated by isoallo-lithocholic acid.
Researchers discovered liver resident macrophages' pivotal role in defending against gut bacteria and related substances entering via the portal vein, particularly under compromised intestinal barrier conditions. Identified as 'sentinel macrophages,' they are activated by isoallo-lithocholic acid.
The liver and intestines are directly connected via the portal vein, a blood vessel that transports nutrients absorbed in the intestines directly to the liver. The intestines harbor numerous gut bacteria, and sometimes these bacteria and their related substances can enter the liver through the portal vein.
Metabolic dysfunction--associated steatohepatitis or MASH is an inflammatory, liver-scarring disease that affects 1.5% to 6.5% of all U.S. adults. ... Behind Enemy Lines: Research Finds a New Ally in the Fight Against Cardiovascular Disease Hidden Within the Vessel Wall Itself
Gastrointestinal Problems Colitis Ulcers Chronic Illness Diseases And Conditions Crohn's Disease Medical Topics
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