A study led by UCLA Health Jonsson Comprehensive Cancer Center researchers found that using a combination of experimental immunotherapy drugs with chemotherapy significantly improves progression-free survival and overall survival for patients with metastatic colorectal cancer who have previously undergone standard chemotherapy treatment when...
May 24 2024University of California - Los Angeles Health Sciences Findings A study led by UCLA Health Jonsson Comprehensive Cancer Center researchers found that using a combination of experimental immunotherapy drugs with chemotherapy significantly improves progression-free survival and overall survival for patients with metastatic colorectal cancer who have previously undergone standard chemotherapy treatment when compared to those who received the targeted therapy regorafenib alone.
The results of the study also showed treatment with the novel combination therapy either partially or completely shrank tumors in 17.3% of patients. For patients on regorafenib only, 2.7% had tumor shrinkage. The team enrolled 112 participants with metastatic colorectal cancer who had previously undergone treatment with oxaliplatin and irinotecan-containing regimens in the Phase Ib/II trial. The patients were randomized into two groups: 75 receiving the EZFB combination and 37 receiving regorafenib alone.
Colorectal Colorectal Cancer Chemotherapy Drugs Immunotherapy Oncology Regorafenib
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