SARS-CoV-2 studies: Only neutralizing antibodies allow conclusions to be drawn about protection against new infections
Principle of cell-culture-based neutralization assays. Conventional virus-neutralization test and pseudovirus-neutralization test are laboratory methods primarily used for identifying whether neutralizing antibodies against SARS-CoV-2 are present in the patient sample. Both tests involve incubating patient serum with the virus or pseudovirus , and then inoculating onto cell culture. If NAbs are present and the virus is neutralized, the cells will not be infected.
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