Globally, around 2.6 million children and adolescents are currently living with HIV, the majority of them in Africa.
University of BaselJul 18 2024 These young people are much more likely to experience treatment failure than adults. Experts long assumed that testing for viral drug resistance could improve treatment in cases where treatment has failed. However, a research team led by the University of Basel, Switzerland, now shows that it is much more important to support patients in taking their medication regularly.
In light of limited funding for HIV programs in a number of African countries, discussions are ongoing among experts on whether treatment success could be improved by providing more resistance tests, particularly for children and adolescents. The researchers divided the patients at random into two groups. One group underwent tests by specialist staff for viral mutations that confer resistance. The second group received the usual care, with repeated viral load testing and empirical treatment.
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