Inflammation-associated gut microbiome in postacute sequelae of SARS-CoV-2 points towards new therapeutic targets

United Kingdom News News

Inflammation-associated gut microbiome in postacute sequelae of SARS-CoV-2 points towards new therapeutic targets
United Kingdom Latest News,United Kingdom Headlines
  • 📰 medical_xpress
  • ⏱ Reading Time:
  • 14 sec. here
  • 2 min. at publisher
  • 📊 Quality Score:
  • News: 9%
  • Publisher: 51%

Researcher identifies potential cause of 'long COVID' CUAnschutz PLOSPathogens

Plasma levels of IL-6 and CRP measured by ELISA and separated by cohort. The difference between cohorts was determined by Mann-Whitney tests. PCoA decomposition of unweighted UniFrac distances for PASC and RC participants. Relationships between PC1 from and circulating levels of IL-6 and CRP for PASC and RC. Statistical significance was measured using linear regression . Each point represents data from one participant where teal represents PASC and orange represents RC.

The groups of taxa that form the global balance are specified at the top of the plot. The box plot represents the distribution of the balance scores for PASC and RC individuals. ROC curve with its AUC value for differentiation PASC from RC based on the balance in E.

We have summarized this news so that you can read it quickly. If you are interested in the news, you can read the full text here. Read more:

medical_xpress /  🏆 101. in UK

United Kingdom Latest News, United Kingdom Headlines

Similar News:You can also read news stories similar to this one that we have collected from other news sources.

SARS-CoV-2 escape from cytotoxic T cells during long-term COVID-19 - Nature CommunicationsSARS-CoV-2 escape from cytotoxic T cells during long-term COVID-19 - Nature CommunicationsHere, the authors report accelerated intrahost evolution of SARS-CoV-2 in an immunocompromised patient with non-Hodgkin’s lymphoma with 318 days long COVID-19, and show that changes in the viral genome resulted in escape from T cellular immune response.
Read more »

SARS-CoV-2 infection and Ad26.COV2.S vaccination may increase risk of stroke post-vaccinationSARS-CoV-2 infection and Ad26.COV2.S vaccination may increase risk of stroke post-vaccinationSARS-CoV-2 infection and Ad26.COV2.S vaccination may increase risk of stroke post-vaccination medrxivpreprint EmoryUniversity SARSCoV2 COVID19 StrokeRisk PostVaccination
Read more »

Omicron variant of SARS-CoV-2 is less infectious in dogs and catsOmicron variant of SARS-CoV-2 is less infectious in dogs and catsOmicron variant of SARS-CoV-2 is less infectious in dogs and cats Coronavirus Disease COVID Omicron Cats Dogs Feline Canine biorxivpreprint Loeffler_News
Read more »

Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients - Nature CommunicationsBroadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients - Nature CommunicationsHere, Rouet et al. present a strategy for the identification of broadly neutralising antibodies against SARS-CoV-2 receptor binding domain from peripheral blood mononuclear cells of convalescent patients, which enabled the identification of a new class 6 epitope.
Read more »

Malaria and the incidence of COVID-19 in Africa: an ecological study - BMC Infectious DiseasesMalaria and the incidence of COVID-19 in Africa: an ecological study - BMC Infectious DiseasesBackground It has been shown that stimulation of innate immunity may provide temporary protection against a variety of infectious diseases. Malaria has been shown to induce a robust innate immune response. This study was conducted to test the hypothesis that if the cumulative number of cases diagnosed with COVID-19 per 100,000 population was correlated with the prevalence of malaria in African countries where both malaria and COVID-19 were prevalent. Methods In this ecological study, the cumulative incidence of COVID-19 and the prevalence of malaria were compared in 53 African countries. A negative binomial regression analysis with the cumulative incidence of COVID-19 as the dependent variable, and the human development index (HDI) and the prevalence of malaria, as independent variables, were used. Results The mean cumulative incidence of COVID-19 was 522 cases per 100,000. Each 0.1 unit increase in HDI was associated with 2.4-fold (95% confidence interval 1.8–3.1) increase in the cumulative incidence of COVID-19. Prevalence of malaria was also independently associated with the cumulative incidence; each 10% increase in the prevalence was associated with 28% (10–41%) decrease in the cumulative incidence of COVID-19. Conclusions Malaria might protect people against SARS-CoV-2 through the stimulation of innate immunity. Stimulation of the innate immune system could be the first line of defense in the pandemic preparedness arsenal.
Read more »

Omicron BQ and XBB subvariants most resistant viruses to monoclonal antibodiesOmicron BQ and XBB subvariants most resistant viruses to monoclonal antibodiesA recent study examines the neutralization of SARS-CoV-2 Omicron sub-variants by sera from boosted individuals and those with breakthrough infection.
Read more »



Render Time: 2025-02-25 19:14:01