IBD, the umbrella term for Crohn’s disease and ulcerative colitis, impacts millions of people worldwide. Researchers say they have found a “major cause' of the disease and treatment using existing drugs.
About 5% of the world’s population, including an estimated 3.1 million adults in the U.S., suffer from inflammatory bowel disease – the umbrella term for Crohn’s disease and ulcerative colitis.People with IBD are more likely to have other chronic conditions and sleep less than 7 hours a day, according to the U.S. Centers for Disease Control and Prevention.
" "Strikingly, simply increasing the amount of ETS2 in resting macrophages turned them into inflammatory cells that closely resembled those from IBD patients," the release noted. The researchers also found that many other genes previously linked to IBD are part of the ETS2 pathway, "providing further evidence that it is a major cause of IBD.
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