Inhaled Insulin Plus Degludec an Option for Type 1 Diabetes

Diabetes Mellitus Type 1 News

Inhaled Insulin Plus Degludec an Option for Type 1 Diabetes
Diabetes Mellitus Type IType 1 DiabetesType 1 DM
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Use of premeal Afrezza insulin plus long-acting degludec insulin was non-inferior to automated insulin delivery or multiple daily-injection regimens, but it isn't for everyone.

. People with type 1 diabetes who use it also need basal insulin, most often taken as a long-acting injected insulin analog such as degludec . Afrezza is taken before or shortly after a meal.

The story, he explained, is told in the secondary endpoints. The proportions of study participants who achieved A1c levels below the recommended 7% were 30% with Afrezza vs just 17% with usual care. And, 21% of those on Afrezza had A1c improvements of 0.5% or greater vs just 5% on usual care. The participants whose glycemia worsened were the ones who tended to bolus less often, Hirsch explained during the briefing.

This aligns with the clinical experience of Viral Shah, MD, professor of medicine and director of diabetes clinical research at the Center for Diabetes and Metabolic Diseases, Indiana University School of Medicine, Indianapolis. Asked to comment on the study in general, Shah said the fact that there was no difference in A1c shows that people are able to use Afrezza properly."It was a non-inferiority trial. For people who don't want to wear a pump, that's an encouraging result."Also discussed at length during the meeting symposium was the discovery, as the study progressed, that higher doses of Afrezza were neededAfrezza comes in cartridges of 4, 8, and 12 units.

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Diabetes Mellitus Type I Type 1 Diabetes Type 1 DM T1DM T1D Insulin Therapy Insulin Pump Continuous Subcutaneous Insulin Infusion Exercise Physical Activity Healthcare And Medical Technology Health And Medical Tech Health And Med Tech Health And Medical Technology Healthcare Technology Medical Technology Diabetes Mellitus Type 2 Diabetes Mellitus Type Ii

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