Innovative tool enhances the accuracy of predicting survival outcomes for liver failure patients

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Innovative tool enhances the accuracy of predicting survival outcomes for liver failure patients
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Researchers have unveiled a groundbreaking advancement in liver failure care: the CATCH-LIFE-MELD score (Chinese Acute-on-Chronic Liver Failure Consortium (CATCH-LIFE)-MELD score).

First Hospital of Jilin UniversityNov 26 2024 Researchers have unveiled a groundbreaking advancement in liver failure care: the CATCH-LIFE-MELD score -MELD score). This innovative tool, developed by an international team led by Xia Yu and colleagues, enhances the accuracy of predicting short-term survival outcomes for patients suffering from acute-on-chronic liver failure .

This refined tool was tested in over 750 patients across two large cohorts, demonstrating superior predictive accuracy for 28- and 90-day mortality compared to traditional models. It also remained robust across subgroups, including patients with hepatitis B, cirrhosis, and varying degrees of organ failure.

Why it matters ACLF is a severe complication of chronic liver disease, marked by rapid organ failure and a high risk of death. While liver transplantation is a potential lifesaver, the shortage of donor organs necessitates accurate risk stratification to prioritize care. The CATCH-LIFE-MELD score's enhanced precision could improve patient outcomes and resource allocation.

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