The investigational drug elinzanetant significantly reduces the frequency and severity of hot flashes associated with menopause while improving women's quality of life, new UVA Health research published in the prestigious Journal of the American Medical Association shows.
University of Virginia Health SystemAug 22 2024 The investigational drug elinzanetant significantly reduces the frequency and severity of hot flash es associated with menopause while improving women's quality of life, new UVA Health research published in the prestigious Journal of the American Medical Association shows.
The women who received elinzanetant reported rapid improvements in their symptoms and quality of life. The trials revealed statistically significant reductions in hot flash frequency and severity within the first week in both trials. At the same time, sleep quality and overall quality of life improved in both trials by week 12.
"There is a huge unmet need for new treatments for hot flashes.
In addition to evaluating the drug's effect on hot flashes, sleep disruptions, and quality of life, the researchers also looked for potential side effects. Headache and fatigue were the most common, and these were mild. Importantly, there were no severe side effects, which is reassuring for the drug's safety.
Estrogen Fatigue Frequency Hormone Medicine Menopause Placebo Research Sleep
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