itemprop=description content=In a comprehensive meta-analysis published in Scientific Reports, researchers unveil a significant link between human papillomavirus (HPV) infection and increased risk of prostate cancer, highlighting the importance of considering normal prostate tissues over benign prostatic hyperplasia (BPH) as controls for more accurate conclusions.
By Dr. Priyom Bose, Ph.D.Oct 8 2023Reviewed by Benedette Cuffari, M.Sc. In a recent Scientific Reports study, scientists conducted a meta-analysis to examine the role of human papillomavirus in prostate carcinogenesis.
Some risk factors associated with prostate cancer include age, genetic predisposition, and family history. Previously, researchers have reported that HOXB13 mutation increases the risk of prostate cancer. Other genes associated with prostate cancer include BRCA1, BRCA2, and the MSH2 gene. Although HPV is associated with cervical cancer in women, it does not appear to increase the risk of ovarian and endometrial cancer.
Nevertheless, some studies have contradicted the idea of HPV being associated with the incidence of prostate cancer. Thus, the exact role of HPV in prostate cancer incidence is unclear. These studies included analyses of 1,607 prostate tumor tissue samples and 1,443 control samples. The tumor prostrate sample was considered the study sample, whereas normal prostate and benign prostatic hyperplasia tissues were considered the control.
BPH samples have a quantitative advantage compared to normal tissue, as HPV detection frequency in BPH is higher. Therefore, no significant association between HPV infection and BPH was found in these studies.
United Kingdom Latest News, United Kingdom Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Fortuna reports record gold production in Q3Record production driven by Séguéla mine
Read more »
Heathrow passengers 'rushed off plane' after reports of 'toxic fumes'Emergency services were called to the airport earlier today.
Read more »
Heathrow passengers 'rushed off plane' after reports of 'unknown fumes'Emergency services were called to the airport earlier today.
Read more »
Man hospitalised with 'serious injuries' after being attacked by up to 30 malesPolice were called to reports of a group of males armed with knives
Read more »
Reports of dog attacks increase in Notts with 31% riseFreedom of Information requests were made to all police forces in England, which found attacks in the county had risen by 31 percent compared to 2022
Read more »