Is vaginal microbiota transfer intervention for infants delivered by C-section beneficial to their neurodevelopment?

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Is vaginal microbiota transfer intervention for infants delivered by C-section beneficial to their neurodevelopment?
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Is vaginal microbiota transfer intervention for infants delivered by C-section beneficial to their neurodevelopment? cellhostmicrobe csection neurodevelopment microbiota microbiome

By Bhavana KunkalikarJun 19 2023Reviewed by Danielle Ellis, B.Sc. In a recent study published in the Cell Host Microbe, researchers examined the impact of vaginal microbiota transfer on the neurodevelopment of infants born via cesarean section .

Neurodevelopment was assessed for 57 infants at six months and 46 infants at three months using the Ages and Stages Questionnaire, Third Edition, . The ASQ-3 consists of five subdomains, including gross motor, communication, problem-solving, personal-social skills, and fine motor. Results The study found that most clinical features were similar between the VMT and Con cohorts, except the VMT group had a lower gestational age than the Con group. The mean maternal age in the VMT group was 31.88 ± 4.32 years, while that in the Con group was 31.67 ± 5.03 years. Prophylactic antibiotics were administered to all C-section mothers following the removal of vaginal fluid gauze.

At the three-month mark, the VMT group had a significantly higher ASQ-3 total score compared to the Con group. Also, at three months, infants who received VMT had higher scores in the communication and gross motor subdomains of ASQ-3 compared to those who did not receive VMT. Furthermore, the VMT group had a notably higher gross motor subdomain score than the Con group at six months.

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