More hospitals and clinics now offer patients ketamine therapy for severe depression, post-traumatic stress disorder and other mental health conditions that haven't responded to other treatments.
Michigan Medicine - University of MichiganSep 3 2024 More hospitals and clinics now offer patients ketamine therapy for severe depression, post-traumatic stress disorder and other mental health conditions that haven't responded to other treatments.
In all, they found a wide variation in policies, practices and warnings about ketamine use related to pregnancy and reproduction. This is despite the fact that the 119 clinics that answered the survey report treating a total of more than 7,000 patients with ketamine per month, and estimate that a third of patients they serve are female and pre-menopausal.
When it came to contraception counseling, only 26% of the clinics that answered the survey said they discuss the potential need for contraception with ketamine patients. Less than 15% of the clinics specifically recommend or require contraception use during treatment. Patients who were pregnant or had recently given birth asked her about ketamine as an option for their treatment-resistant depression. They had heard of the potential positive impact of the drug when given intravenously as an off-label use of a common anesthetic, or as an intranasal spray of esketamine that's marketed as Spravato and approved by the U.S. Food and Drug Administration.
The new study did not include online, direct-to-consumer ketamine providers that offer treatment exclusively via telehealth consultations. It is unknown how these companies address reproductive and other safety concerns despite their growing popularity among patients. "The variability in practice that we see among clinics in the community in this study is stark," said Pacilio. "The field is really in need of standardization around reproductive counseling, pregnancy testing and the recommendation for contraception during ketamine treatment."
Pregnancy Contraception Depression Health Clinic Medicine Mental Health Post-Traumatic Stress Disorder Psychiatry Reproduction Research Stress
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