Largest ALS patient-based iPSC repository opens new frontiers in research

Amyotrophic Lateral Sclerosis News

Largest ALS patient-based iPSC repository opens new frontiers in research
BloodCellGenetic
  • 📰 NewsMedical
  • ⏱ Reading Time:
  • 65 sec. here
  • 12 min. at publisher
  • 📊 Quality Score:
  • News: 60%
  • Publisher: 71%

In a landmark continuing collaboration, Answer ALS and Cedars-Sinai have announced the completed availability of the largest amyotrophic lateral sclerosis (ALS) patient-based induced pluripotent stem cell (iPSC) and bio data repository.

Answer ALSNov 15 2024 In a landmark continuing collaboration, Answer ALS and Cedars-Sinai have announced the completed availability of the largest amyotrophic lateral sclerosis patient-based induced pluripotent stem cell and bio data repository. The repository encompasses biological and clinical data from nearly 1,000 ALS patients, offering an unprecedented resource for global researchers studying ALS, commonly known as Lou Gehrig's disease.

We reprogrammed blood cells into iPSCs and differentiated them into motor neurons, which die in ALS patients at an unprecedented scale. This has established the world's largest bank of specialized neurons for ALS research to date and offers a comprehensive and advanced model for disease research and drug discovery." This approach enables investigators across academia and industry to access a vast array of patient-specific iPSCs and differentiated motor neurons.

These data and links to the associated bio-resources are made available to the global research community through the Answer ALS Neuromine Data Portal, and Cedars-Sinai Biomanufacturing Center, which serves as a crucial tool for researchers, offering access to a wide array of patient-specific iPSCs and the data inherent in these cells.

The repository has already distributed over 1,800 cell lines to over 130 entities, including universities and pharmaceutical companies both domestically and internationally. By making the Answer ALS data continuously available through an online, open-source portal, the repository ensures that the data from every sample is accessible to scientists worldwide, enhancing the collective effort to decipher ALS pathology and develop targeted therapies.

We have summarized this news so that you can read it quickly. If you are interested in the news, you can read the full text here. Read more:

NewsMedical /  🏆 19. in UK

Blood Cell Genetic Medicine Motor Neurons Neurons Ph Research Sclerosis

United Kingdom Latest News, United Kingdom Headlines

Similar News:You can also read news stories similar to this one that we have collected from other news sources.

Couples face cut to largest inheritance tax exemption in Reeves’s BudgetCouples face cut to largest inheritance tax exemption in Reeves’s BudgetThe spousal exemption benefit often has the biggest impact for some of the wealthiest in society
Read more »

People struggling to answer the 'strangest' GCSE maths question everPeople struggling to answer the 'strangest' GCSE maths question everGCSE exams are known for being stressful with many of us, thankfully, never facing such test questions again post-graduation - which is perhaps why lots of us are baffled by one particular question
Read more »

Leeds man arrested in largest-ever crackdown on human traffickingLeeds man arrested in largest-ever crackdown on human traffickingNational Crime Agency makes arrests in West Yorkshire during people smuggling Interpol crackdown
Read more »

Man who made largest GPS drawing of a penis calls it 'hardest thing I’ve done'Man who made largest GPS drawing of a penis calls it 'hardest thing I’ve done'Terry Rosoman trekked through mist and pitch-black conditions across the Brecon Beacons in a 75-mile phallus-shaped route to raise awareness of men's mental health.
Read more »

Filming the world’s largest goats in PakistanFilming the world’s largest goats in PakistanAsia's wildest places, from the Siberian wilderness to the coral seas of the Indian Ocean.
Read more »

People just discovering where to store ketchup as experts weigh in with right answerPeople just discovering where to store ketchup as experts weigh in with right answerThe debate has been ongoing for years, and now, the consumer experts at Which? have settled the argument once and for all
Read more »



Render Time: 2025-04-07 00:51:12