Long COVID Research Is In Its ‘Most Hopeful’ Phase Yet

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Long COVID Research Is In Its ‘Most Hopeful’ Phase Yet
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Researchers are getting closer to understanding how to diagnose and treat people with Long COVID.

A phenomenal amount of research on Long COVID—the name for chronic symptoms following a case of COVID-19—has been published over the past three years. But scientific advances have yet to bring relief to people who are already sick, a group, and several recent studies have pointed to biomarkers that may help doctors accurately diagnose—and, hopefully, treat—people with Long COVID.

Co-author Akiko Iwasaki, an immunobiologist who directs Yale University School of Medicine's Center for Infection and Immunity, says it's unlikely there will ever be a single biomarker for Long COVID, since the disease can look very different from person to person. But when a machine-learning model was trained to pick up on all of those potential signals together, it was able to distinguish the blood of Long COVID patients from the blood of people without the condition with 96% accuracy.

The study is important because it “gets us closer to understanding what’s happening” in the bodies of people with Long COVID, says Hannah Davis, one of the leaders of the Patient-Led Research Collaborative for Long COVID.

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