The lung ciliary beat frequency analysis in vitro assay assesses the effect of drugs on the function of cilia in the small airway epithelium.
To aid in assessing the impact of chemicals and drugs on cilia function in the small airway epithelium, the lung cilia beat frequency analysisUsing the physiologically relevant lung small airway epithelial cell model in air-liquid interface culture, the assay accurately predictsresults.
Obtain quick and reliable study data that provides critical insights into the impact of compounds on cilia activity of lung small airway cells by utilizing Newcells' high-sensivity ciliary beating assay serviceThe ciliary beat frequency analysis assay can detect frequency alterations as low as 0.25 Hz and identify the most efficacious compounds to proceed throughout drug development.
Validation of COPD-like conditions is demonstrated by changes in percentage area covered by active cilia and ciliary beat frequency due to IL-13 treatment of SAEC cultures is demonstrated through the heatmaps and ciliary beat frequency Percentage area covered by active cilia and Integrated Cilia activity with changing IL-13 concentrations generated using CiliaBeat software.
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