Marshall University was awarded a $3.3 million grant (#R01DA057931) from the National Institute on Drug Abuse (NIDA) to examine the genetic mechanisms that underlie fentanyl addiction.
Marshall University Joan C. Edwards School of Medicine Jul 19 2024 Marshall University was awarded a $3.3 million grant from the National Institute on Drug Abuse to examine the genetic mechanisms that underlie fentanyl addiction.
This alarming statistic highlights the urgent need to understand why some people are more susceptible to fentanyl addiction. Identifying how certain genes influence the brain's response to fentanyl will pave the way for the development of effective treatments, thus addressing a critical public health need."
According to the incentive sensitization theory of addiction, repeated drug use can make the brain's reward system overly sensitive to drug-related cues, leading to a powerful craving for the drug. While both fentanyl addiction and incentive sensitization are known to be highly inheritable in humans and mice, the specific genetic mechanisms linking incentive sensitization to fentanyl addiction have remained elusive.
Fentanyl Research Brain Drug Abuse Genes Genetic Medicine Neuroscience Overdose Ph Public Health
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