The study population included nearly 1.3 million children born in Quebec, Canada, over a 16-year period.
is associated with an increased risk for adverse birth outcomes and childhood morbidities, including respiratory, metabolic, central nervous system, and other conditions.
"HS is associated with morbidity in women of reproductive age and adverse pregnancy outcomes, its effect on offspring outcomes remains unclear," corresponding author Kaiyang Li, a third-year medical student at McGill University, Quebec, Canada, and co-authors wrote in their abstract. Next, they estimated hazard ratios and 95% CIs for the association of maternal HS with childhood morbidity in adjusted Cox proportional hazards regression models. "As prenatal exposure toThe study population included 1283 children whose mothers had HS and 1,274,310 unexposed children. As for infant outcomes, compared with no exposure, maternal HS was associated with an increased risk for, neonatal death , birth defects , congenital heart defects , and orofacial defects .
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