Maternal cardiometabolic health during pregnancy is associated with child developmental outcomes at 5 years old, finds a study published in BMCMedicine.
] have described associations between pregnancy cardiometabolic markers and childhood health-related outcomes, it still remains unclear whether the associations are predominantly due to intrauterine mechanisms or other external confounders such as birth outcomes or socioeconomic levels. The mediation models in this study provides a closer examination of maternal-child associations with added mediators before any environmental influence.
This study had several limitations. First, this prospective cohort had a limited sample size that met the requirement for metabolic syndrome classification , in addition to missing data for the child cord blood markers when comparing mother–child pairs. In addition, the measure of diabetes taken by the study team did not differentiate between type I and type II diabetes in the mother.
Future research could include a closer examination of ethnic differences, epigenetic effects, or additional childhood factors such as feeding or sleeping and environmental factors contributing to maternal cardiometabolic health and child developmental outcomes.
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