Researchers evaluated health-related quality of life and other outcomes in patients taking medicinal cannabis.
By Tarun Sai LomteSep 11 2023Reviewed by Sophia Coveney In a recent study published in PLOS ONE, researchers evaluated health-related quality of life and other outcomes in patients taking medicinal cannabis .
There is limited data on how medical cannabis affects HRQL; therefore, real-world evidence is required to investigate the changes in HRQL with medical cannabis usage and inform policy-making and regulation. Medical cannabis oil products were phytocannabinoids in a medium-chain triglyceride carrier oil. Data on patient demographics, clinical characteristics, medical cannabis prescriptions, and health conditions treated with medical cannabis were collected.
The team calculated means, standard deviations, and effect sizes for each time point. Linear regression was used on QLQ-C30 scores to assess baseline differences in patient characteristics. Linear mixed models examined the change in PRO scores over time. Changes in DASS severity categories over time were analyzed using the chi-squared test.
The average QLQ-C30 summary and EQ-5D-5L index scores increased by 10.7 and 0.15 points from baseline to mean follow-up, respectively, implying a clinically meaningful improvement. Similarly, QLQ-C30 pain scores displayed significant improvement trends, increasing by 16.51 points from baseline to mean follow-up, indicative of clinically meaningful change. There was no evidence of changes in sleep disturbance.
United Kingdom Latest News, United Kingdom Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Musashi-2 protein plays key role in the regulation of mass and metabolic processes in skeletal muscleResearchers from Tokyo Metropolitan University have shown that the protein Musashi-2 (Msi2) plays a key role in the regulation of mass and metabolic processes in skeletal muscle.
Read more »
Mental health worsens as credit crunch bites, with youngest hardest hitAlmost half of 25 to 34-year-olds said their mental health had deteriorated, researchers found, as rents rise at highest rate since 2016
Read more »
Scientists identify new therapeutic target for metastatic cancerIn a recent study led by Lei Jiang, Ph.D., an assistant professor of molecular and cellular endocrinology, a team of researchers from City of Hope and the University of Texas Southwestern Medical Center, found a potential new target for treating patients with metastatic cancer. Their findings were published in the August 29 issue of the journal Cell Reports.
Read more »
Blood test for chronic fatigue syndrome found to be 91% accurateAn international team of medical researchers has announced the development of a blood test for chronic fatigue syndrome. The test is reportedly 91% accurate. In their paper published in the journal Advanced Science, the group describes their test, how it works and how well it has fared during initial testing.
Read more »
Unlocking the secret drivers of deadly pancreatic cancer: New target offers hope for treatmentResearchers identify a super-enhancer-regulated RNA-binding protein cascade that drives the growth of pancreatic ductal adenocarcinoma, a deadly form of pancreatic cancer. The discovery offers a promising new avenue for targeted therapy, potentially sidestepping severe side effects associated with other treatments.
Read more »
Unlocking the secrets of our body's first line of defense against strep throat and moreResearchers have mapped the complex structures of secretory immunoglobulin A (sIgA) in interaction with human CD89 and Streptococcus pyogenes M4, offering new insights into how our first line of mucosal defense operates. The study reveals the intricate ways these components may influence each other, impacting both bacterial survival strategies and host immune responses.
Read more »