A rare genetic condition that causes short stature may also provide protection from diabetes, heart disease and other illnesses, a new study says.
In the Los Angeles restaurant where Nathaly Paola Castro Torres works, customers never fail to comment on her short stature. “People stare at me too much and make comments or jokes,” Torres, 42, said. “Many times they also photos of me and I don’t like it. I feel very bad.” At 4 feet, 2 inches tall , Torres is a “little person” who isn’t used to such reactions. While she was growing up in Quito, Ecuador, people seldom mentioned her height.
“The idea would be for people who have high circulating IGF-1 levels to get drugs that lower the IGF-1 back to the range that seems to be associated with the lowest mortality rate, much like people take a drug for high cholesterol,” Longo said. A Western diet packed with protein and sugar also increases circulating levels of IGF-1, thus hastening aging, Longo said. “There are IGF-1 lowering diets, such as fasting for five days a month, which is called a fasting-mimicking diet,” he said.
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