Mighty mutant mice maintain muscle mass in space

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Mighty mutant mice maintain muscle mass in space
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The mice, launched to the International Space Station on a SpaceX rocket, were experimented on with a new muscle-enhancing drug.

Mutant mice sent to the International Space Station on a SpaceX rocket returned to Earth maintaining their significant muscle mass thanks to an experimental drug, scientists have revealed.

The research offers hope for astronauts who usually lose a significant amount of bone and muscle mass while in zero-gravity environments, as well as people on Earth confined to beds or wheelchairs. Scientists sent 40 young female black mice to the ISS last December, where they were tended to by astronauts Jessica Meir and Christina Koch in an experiment with a novel treatment designed to prevent muscle and bone loss.The regular mice sent into space lost up to 18% of their mass due to the zero-gravity environment, according to the paper published in the Proceedings of the National Academy of Sciences.

But eight genetically engineered"mighty mice", with double the muscle of their fellows, managed to maintain their mass at a level comparable to mice which remained on Earth at NASA's Kennedy Space Centre.Even more startlingly, eight other normal mice that were not genetically engineered, but that were given doses of the"mighty mouse" drug, returned to Earth with dramatically bigger muscles.

Some of the ordinary mice that returned from the ISS in January were then injected with the drug after being brought back to the Kennedy Space Centre - and again quickly developed more muscle than mice which went untreated.

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