Study participants saw a reduction in cardiovascular disease risk factors and biological age despite a moderate calorie restriction of 12%.
The CALERIE participants saw a reduction in cardiovascular disease risk factors and biological age despite a moderate calorie restriction of 12%.Study finds that low-calorie diet can significantly reduce biological aging such the Buddha bowl with fresh vegetables in the image.Scientists have been trying to predict an individual’s biological age to promote healthy aging by identifying early signs of unhealthy aging.
“We found signatures of metabolic dysregulation, cardiac and renal dysfunction, and inflammation that predict unsuccessful aging, and we demonstrate that these processes can be impacted using well-established drug interventions,” the authors stated. “We generated a streamlined aging clock , based directly on PCAge, which maintains equivalent predictive power but relies on substantially fewer features,” the authors added.
“Our analysis of CALERIE participants suggests that two years of mild caloric restriction significantly reduces biological age.”
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