Reproductive aging in Caenorhabditis elegans is regulated through an interaction of the metabolism of mitochondrial guanosine-triphosphate.
By Dr. Chinta SidharthanSep 18 2023Reviewed by Lily Ramsey, LLM In a recent study published in the Developmental Cell Journal, researchers reported that reproductive aging in Caenorhabditis elegans is regulated through an interaction of the metabolism of mitochondrial guanosine-triphosphate and factors involved in mitochondrial dynamics.
Of all the cells in the body, oocytes have the highest number of mitochondria. Consequently, mitochondrial activity is believed to be the most important contributor to changes in oocyte quality. About the study In the present study, the researchers used C. elegans as a model system to understand the role of mitochondrial dynamics in reproductive aging.
However, in C. elegans, the selective overexpression of drp-1, the DRP1 homolog, in the intestine, or the whole-body knockout of drp-1 and the homolog of MFN in C. elegans — fuzzy onions related -1 — results in an increase in lifespan.
United Kingdom Latest News, United Kingdom Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Taylor ready to “take risks” in IMSA GTP title showdown racesRicky Taylor and co-driver Filipe Albuquerque have found themselves in somewhat of a paradox as the GTP point leaders with two rounds remaining of the IMSA SportsCar Championship.
Read more »
Taylor ready to “take risks” in IMSA GTP title showdown racesRicky Taylor and co-driver Filipe Albuquerque have found themselves in somewhat of a paradox as the GTP point leaders with two rounds remaining of the IMSA SportsCar Championship.
Read more »