Monkeypox infection in a smallpox-vaccinated patient Monkeypox Smallpox CDC_NCEZID MadiganHealth
In Summer 2022, the Centers for Disease Control and Prevention initiated an emergency response after the outbreak of monkeypox infections across the US. In addition, on 28 June 2022, the US Department of Health and Human Services announced a vaccination strategy against the monkeypox virus to be implemented across the country.
Patient characteristics In the present study, the team reported a patient residing in Washington, USA, who was infected with the monkeypox virus. However, he was successfully vaccinated against smallpox with the ACAM2000 smallpox vaccine eight years before. The patient reported a history of syphilis and N. gonorrhea in 2017 that was resolved after treatment. His military health records did not show any history of human immunodeficiency virus infection or other immunocompromising conditions. He was previously recommended daily treatment with emtricitabine/tenovir as a pre-exposure prophylactic measure against HIV. However, he self-discontinued this treatment a year before he sought medical care.
Results The study results showed that the patient displayed four ulcerated penile lesions that had progressed into a patch on the foreskin. This patch was observed two days after the patient developed constitutional symptoms. The lesions were non-tender, with no discharge observed. A tender right inguinal lymph node was also observed, along with a vaccination scar on his right deltoid.
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