Research shows that increasing the plant-to-animal protein ratio in diets may lower cardiovascular disease and coronary artery disease risks, excluding stroke.
By Dr. Priyom Bose, Ph.D.Reviewed by Danielle Ellis, B.Sc.Dec 6 2024 A higher plant-to-animal dietary protein ratio is associated with lower risks of cardiovascular disease and coronary artery disease , but not stroke
Research has not yet documented the optimal ratio of animal and plant protein intake in the diet for CVD prevention. The lack of evaluation of the optimal ratio has led to an absence of recommendations concerning the relative contribution from these sources of protein. Therefore, public health guidance on protein sources can be refined by assessing ratios of the plant-to-animal protein.
CVD was defined as a composite of CAD, incident non-fatal myocardial infarction , and fatal and non-fatal stroke. Death was confirmed by the National Death Index, relatives, or postal authorities. An array of covariates was considered, including medical history, family history, lifestyle, reproductive factors, medication use, and so on.
Concerning the dose dependence, a significant risk reduction was noted early in the dose-response curve, followed by more gradual reductions. For stroke, no evidence of linear or nonlinear associations was noted. When higher P: A ratios were combined with higher protein density, the inverse associations with CVD and CAD were stronger. The results were largely consistent in sensitivity and sub-group analyses.
Heart Disease Protein Stroke Cardiovascular Disease Coronary Artery Disease Diet Food Nutrition Research
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