The prevalence of inflammatory bowel disease in U.S. children under 20 is increasing, with over 100,000 affected, revealing critical public health concerns.
By Dr. Chinta SidharthanReviewed by Danielle Ellis, B.Sc.Nov 22 2024 A CDC-funded study reveals a growing prevalence of inflammatory bowel disease in Americans under 20, among the highest rates in the world.
Background Inflammatory bowel diseases , including Crohn's disease and ulcerative colitis, are chronic conditions characterized by gastrointestinal inflammation. While traditionally considered rare in children, the prevalence of pediatric IBD has been increasing, especially in high-income regions such as North America. Children with IBD often experience more extensive disease and aggressive progression compared to adults.
About the study The present study pooled data from two commercial insurance datasets and five state Medicaid programs to estimate pediatric IBD prevalence across the U.S. Data sources included de-identified records from Optum's Clinformatics Data Mart, the Healthcare Integrated Research Database from Carelon Research, and Medicaid records from New York, Florida, Pennsylvania, California, and Ohio.
The researchers used direct standardization techniques to produce nationally representative prevalence estimates. They also stratified the data by age, sex, race, ethnicity, and geographic region. To assess temporal changes, they compared prevalence trends from 2011 to 2020, with statistical adjustments accounting for variability in data collection methods across datasets.
The prevalence was found to increase with age and was higher in males for Crohn's disease but not ulcerative colitis. The disease was most common among White children , followed by Black , Hispanic , and Asian children . Additionally, the regional analysis revealed a higher prevalence in the northeastern states than in other areas.
Children Chronic Crohn's Disease Diagnostic Gastroenterology Healthcare Inflammation Medicaid Public Health Research Ulcerative Colitis
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