For folks who have battled alcohol dependency for years, any treatment that could curb or block alcohol cravings would be a huge advance.
A compound -- so far dubbed LY2444296 -- appears to block a key brain cell receptor called the kappa opioid receptor , a team at the Scripps Research Institute in California reports.
In the study, the Scripps team tested the new compound on mice that had become alcohol-dependent. Would LY2444296 ease their cravings? Behaviors of alcohol withdrawal normally exhibited by mice "tapered down significantly," according to the news release. Perhaps, if LY2444296 is taken before withdrawal symptoms begin, “you can decrease the symptoms, so you feel better and drink less," he reasoned.
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