MSU researchers test new nanotherapy infusion to target arterial inflammation

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MSU researchers test new nanotherapy infusion to target arterial inflammation
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Inflammation of the arteries is a primary precursor and driver of cardiovascular disease -; the No. 1 killer of people in the United States. This inflammation is associated with the buildup of dangerous plaque inside the arteries.

Michigan State UniversityOct 10 2024 Advanced treatments are needed to target this inflammation in patients. Michigan State University researchers have tested a new nanoparticle nanotherapy infusion that precisely targets inflammation and activates the immune system to help clear out arterial plaque.

Bryan Smith, Associate Professor, Department of Biomedical Engineering, College of Engineering and MSU's Institute for Quantitative Health Science and Engineering "That's the scarier one that leads to most heart attacks," said Smith. "Because such plaques don't necessarily block much of the artery, and because the effects of the rupture can very suddenly completely block blood flow, such a heart attack can seem to appear as if from nowhere."

Related StoriesPrevious studies by Smith and his collaborators, the Leeper Lab at Stanford University, tested the infusion on mice and now, pig models, to prove the infusion's effectiveness and, critically, its lack of side effects due to its precision immune targeting.

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