It will operate four days a week during the Spring and Summer seasons
The newest Aer Lingus Regional service has taken off for the first time this season from Belfast City Airport.
"Newquay has always been a popular destination for travellers from Northern Ireland and we are pleased to offer passengers a convenient, direct connection to Cornwall and the South of England. Operated by Emerald Airlines, the new route builds on the Aer Lingus Regional existing portfolio from Belfast City Airport with flights already in operation to Birmingham, Cardiff, Edinburgh, East Midlands, Exeter, Glasgow, Leeds Bradford, Manchester, and Southampton.
Commenting on the announcement, Ciarán Smith, Head of Commercial at Emerald Airlines said: "We are delighted to be further strengthening our service offering from Belfast City Airport.