A team of researchers from the University of Barcelona and the Bellvitge Biomedical Research Institute (IDIBELL) has identified a potential biomarker of Parkinson's disease progression.
University of BarcelonaNov 12 2024 A team of researchers from the University of Barcelona and the Bellvitge Biomedical Research Institute has identified a potential biomarker of Parkinson's disease progression. According to the new study, published in the NPJ Parkinson's Disease, patients with a slow progression of the pathology would have a significant increase in the levels of a molecule called ecto-GPR37 in the cerebrospinal fluid.
According to the researcher, patients with rapid progression have an accelerated onset and worsening of symptoms, motor fluctuations and complications, as well as an increased likelihood of cognitive impairment and psychiatric symptoms. In contrast, patients with slow progression have a gradual onset and progression of symptoms and can maintain higher levels of functional ability and for longer periods of time. In addition, they often have milder symptoms, especially in the early stages.
To validate previous findings and test whether this potential biomarker is specific to Parkinson's disease, the researchers have now analysed the processing of GPR37 in the brain and the presence of ecto-GPR37 in the cerebrospinal fluid of patients with Parkinson's, Alzheimer's and also other neurodegenerative diseases with clinical features similar to Parkinson's, such as multiple system atrophy, corticobasal degeneration and progressive supranuclear palsy.
Brain Medicine Molecule Movement Disorders Neurodegenerative Disease Neurodegenerative Diseases Parkinson's Disease Pathology Receptor Research
United Kingdom Latest News, United Kingdom Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Lidl is offering new workers up to £46k a year to go to universityThe scheme is designed to help develop the next generation of retail leaders
Read more »
Jimmy Doherty takes on new role at Anglia Ruskin UniversityJimmy Doherty, who is also a farmer, will help to run education and research projects for students.
Read more »
Grieving couple whose daughter, 20, killed herself at Bristol University call for new 'duty of care'...The heartbroken parents of a 'hard-working and high-achieving' student who took her own life are calling to make duty of care to students a legal requirement for universities
Read more »
Grieving couple whose daughter, 20, killed herself at Bristol University call for new 'duty of care'...The heartbroken parents of a 'hard-working and high-achieving' student who took her own life are calling to make duty of care to students a legal requirement for universities
Read more »
Grieving couple whose daughter, 20, killed herself at Bristol University call for new 'duty of care'...The heartbroken parents of a 'hard-working and high-achieving' student who took her own life are calling to make duty of care to students a legal requirement for universities
Read more »
Manchester Metropolitan University open new state-of-the-art buildingThe John Dalton building will becone the new home for Science and Engineering at the university
Read more »