The candidate vaccine aims to provide enhanced protection against variants of SARS-CoV-2, the virus that causes COVID-19.
A trial sponsored by the National Institutes of Health is recruiting participants to study a nasal COVID-19 vaccine. One goal of the trial is to evaluate the vaccine's ability to produce local immunity in cells lining the nose and respiratory tract and lower the virus's potential to spread.
The candidate vaccine in the clinical trial, MPV/S-2P, uses murine pneumonia virus to deliver a stabilized version of a spike protein that SARS-CoV-2 uses to attach to human cells. By administering it intranasally, researchers aim to have the vaccine produce local immunity in the nose and throat, where infection from respiratory viruses often starts.
SARS-Cov-2 Clinical Trial Coronavirus Covid Covid-19 Health Nasal Sick Vaccination Vaccine Sknd
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