Circadian clocks, which drive circadian rhythms, are entwined with many essential systems in living things including plants, fungi, insects, and even humans. Because of this, disruptions to our circadian clocks are linked to higher disease rates in humans, including certain cancers and autoimmune diseases.
Rensselaer Polytechnic Institute's Jennifer Hurley, Ph.D., Richard Baruch M.D. Career Development Chair and Associate Department Head of Biological Sciences, has dedicated her career to understanding the mechanisms that allow our circadian clocks to keep time.
"We expected a simple, straightforward interaction between FRQ and FRH," said Hurley."And we found the interaction was much more complex than we expected." Health care offers vast opportunities to apply our knowledge of circadian rhythms."Our field refers to this as 'chronotherapy,'" said Hurley."If you get injured at one time of day, you heal much faster than at another. Therefore, we can schedule surgeries at the right time of day. We can even time chemotherapy treatments to when healthy cells are not dividing but cancer cells are, lessoning side effects and increasing treatment efficacy.
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