A recently approved drug for migraine prevention, atogepant, appears to work rapidly, according to a study published in Neurology. The study found that people taking atogepant experienced fewer migraines on the first day of treatment compared to those on a placebo. Benefits continued throughout the four-week study period.
American Academy of NeurologyDec 23 2024 A drug recently approved to prevent migraine may start working right away, according to a study published in the December 23, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study looked at the drug atogepant, which is a calcitonin gene-related peptide receptor antagonist taken by mouth.
In the study, people taking the drug atogepant were less likely to have a migraine on the first day of taking the drug compared to those taking a placebo. They also had fewer migraines per week during each of the first four weeks of the study and fewer migraines during the study overall than those taking a placebo.
On the first day of the study, 12% of those taking the drug in the first trial, the ADVANCE trial had a migraine, compared to 25% of those taking placebo. In the second trial, the ELEVATE trial, the numbers were 15% and 26%. For the third trial, the PROGRESS trial, the numbers were 51% and 61%.
Migraine Drug Prevention Atogepant CGRP
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