Researchers revved up immune cells that shrank an extremely aggressive type of brain tumor when tested in a handful of patients. The experiments are just first…
In Mass General's test, tumors in three patients rapidly began shrinking within a couple of days, the researchers reported in the New England Journal of Medicine —"None of us could really believe it," Dr. Marcela Maus saidA new strategy to fight an extremely aggressive type of brain tumor showed promise in a pair of experiments with a handful of patients.
So-called CAR-T therapy already is used to fight blood-related cancers like leukemia but researchers have struggled to make it work for solid tumors. Now separate teams at Massachusetts General Hospital and the University of Pennsylvania are developing next-generation CAR-T versions designed to get past some of glioblastoma’s defenses.
Sen. John McCain died Saturday, Aug. 25, 2018, at the age of 81. McCain was diagnosed with brain cancer in July 2017. Mass General and Penn each developed two-pronged approaches and tried them in patients whose tumors returned after standard treatment.
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