Brigham researchers found people with wide-ranging long COVID symptoms were twice as likely to have SARS-CoV-2 proteins in their blood, compared to those without long COVID symptoms.
Brigham and Women's Hospital Oct 9 2024
The study analyzed 1,569 blood samples collected from 706 people, including 392 participants from the National Institutes of Health-supported Researching COVID to Enhance Recovery Initiative, who had previously tested positive for a COVID infection. With a highly sensitive test they developed, researchers looked for whole and partial proteins from the SARS-CoV-2 virus.
It's possible that a persistent infection explains some – but not all – of the long COVID sufferers' symptoms. If this is the case, testing and treatment could aid in identifying patients who may benefit from treatments such as antiviral medications. To better understand whether an ongoing infection is behind some people's long COVID symptoms, Swank, Walt and other researchers are currently conducting follow-up studies. They're analyzing blood samples and symptom data in larger groups of patients, including people of wide age ranges and those with compromised immune symptoms. This way, they can also see if some people are more likely to have persistent virus in the body.
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