New study offers hope for extending ovarian healthspan and function

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New study offers hope for extending ovarian healthspan and function
AgingBoneCancer
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A woman's ovaries are like a factory where eggs grow and produce hormones that regulate everything from menstruation and pregnancy to bone density and mood.

Northwestern UniversitySep 17 2024 A woman's ovaries are like a factory where eggs grow and produce hormones that regulate everything from menstruation and pregnancy to bone density and mood. As she and her factory age, production dwindles, and by the time she hits menopause , the factory is preparing to shut its doors.

Francesca Duncan, corresponding author, associate professor of obstetrics and gynecology at Northwestern University Feinberg School of MedicineFor this study, researchers used Pirfenidone, which is commonly used to treat idiopathic pulmonary fibrosis. But other ongoing studies are underway to identify optimal drug targets for ovarian fibrosis and to conduct clinical trials in women.

Stiff ovaries also affect egg quality, the earlier study found, which could help explain why women's fertility declines in their 30s and 40s. 'Pushing the fertile window is not the ultimate goal of the study' Lengthening a woman's fertility window is only one part of the equation, Duncan said.

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