Researchers from the University of Waterloo have developed a new technology that can hold an entire course of antibiotics in one tiny dose and deliver on demand just the right amount of medication that a particular patient needs to fight an infection.
University of WaterlooOct 24 2024
The team from the School of Pharmacy at Waterloo found that this personalized nanomedicine, which attacks bacteria at the molecular level, results in patients taking the exact amount required to fight the infection while reducing the risk of antibiotic resistance. With the misuse and overuse of antibiotics, bacteria strains develop a tolerance, resulting in antimicrobial resistance , a global threat.
"Compared to traditional therapies that release drugs continuously, even when not needed, our nanomedicine is designed to release drugs only when required, which will potentially reduce severe side effects associated with excess dosing," Ho said. "In addition to combatting AMR by ensuring patients take all of their medicine, there would be fewer side effects because they also don't take too much of the drug. Our technology is far-reaching, and this is just the beginning.
There is a high rate of reinfection when treating Gardnerella vaginalis and Streptococcus pneumoniae with antibiotics. The aim was to develop a drug where a patient doesn't have to keep taking multiple doses to prevent reinfection. Ho's goal is to use this technology in the prevention and treatment of many diseases.
Bacteria Bacterial Vaginosis Drug Delivery Drugs Food Meningitis Nanomedicine Pain Pharmacy Pneumolysin Pneumonia Research Sepsis Streptococcus Pneumoniae Technology
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