Researchers at the Centre for Genomic Regulation (CRG) have discovered a treatment which accelerates the production and quality of pluripotent stem cells in mice.
Center for Genomic RegulationAug 7 2024 Research ers at the Centre for Genomic Regulation have discovered a treatment which accelerates the production and quality of pluripotent stem cells in mice. This discovery that has the potential to improve disease modeling and drug testing for individuals with two X chromosomes; women, transgender men or men with an extra X chromosome in Klinefelter Syndrome . The findings are published in the journal Science Advances.
The researchers discovered that adding interferon gamma to a culture of mouse neural precursor cells, a type of cell which turns into different types of neurons, cut the time it takes to reprogram iPSCs by one day, saving time and resources. Dr. Mercedes Barrero, first author of the study and researcher, Centre for Genomic Regulation, Barcelona
Related StoriesThis is because female adult cells usually have one X chromosome dormant, a compensation mechanism which helps avoid the effects of a double dose of gene products from both X chromosomes being active. Male cells with XY chromosomes don't have to deal with this problem.
Protein Chromosome DNA Gene Genomic Induced Pluripotent Stem Cells Interferon Klinefelter Syndrome Medicine Research Stem Cells Syndrome X Chromosome
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