A trial with a large cohort of patients with early-stage, node-negative breast cancer showed that skipping axillary lymph node dissection does not affect recurrence risk or 5-year overall survival outcomes. The study aimed to fill the gaps in the literature and provide more evidence on the topic.
Omitting axillary lymph node dissection does not increase the risk for recurrence or compromise 5-year overall survival outcomes in patients with early-stage, node-negativeA growing body of evidence has indicated that patients with one or two positive sentinel nodes undergoing breast-conserving surgery and radiation therapy can skip axillary lymph node dissection and achieve similar outcomes compared with patients...
To fill the gaps in the literature, the researchers conducted a trial with a large, inclusive cohort of patients with node-negative stage T1-T3 breast cancer who had one or two sentinel-node macrometastases and had undergone a Earlier recurrence-free survival findings and patient-reported outcomes were reported last December. The researchers now reported overall survival findings as well as secondary endpoints of breast cancer-specific survival.The researchers reported 191 recurrences or deaths over a median follow-up of 46.8 months; 62 patients in the sentinel-node biopsy–only group died, and 69 patients in the dissection group died.
Axillary Lymph Node Dissection Recurrence Risk Overall Survival Early-Stage Breast Cancer Node-Negative
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