Once-a-day oral weight loss drug shows promising results in reducing body weight

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Once-a-day oral weight loss drug shows promising results in reducing body weight
AgonistDiabetesGLP-1
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Individuals who received a once-a-day oral weight loss drug lost up to 13% of their body weight over three months, the annual meeting of the European Association for the Study of Diabetes (EASD) in Madrid, Spain (9-13 September) will hear.

DiabetologiaSep 10 2024 Individuals who received a once-a-day oral weight loss drug lost up to 13% of their body weight over three months, the annual meeting of the European Association for the Study of Diabetes in Madrid, Spain will hear.

Currently, GLP-1 based treatment options are mainly administered via injections, a delivery method also used for the amylin-based treatments undergoing clinical development. To date, there are no tablet-form treatment options targeting both of these biologies. In the first-in-human trial, amycretin appeared to have a safe and tolerable profile in line with the drug receptor classes. Side effects were mainly mild to moderate in severity and of gastrointestinal nature including nausea and vomiting.

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Weight loss of up to 13% achieved in three months with once-a-day tablet, Phase I trial findsWeight loss of up to 13% achieved in three months with once-a-day tablet, Phase I trial findsIndividuals who received a once-a-day oral weight loss drug lost up to 13% of their body weight over three months, according to a presentation at the annual meeting of the European Association for the Study of Diabetes (EASD), held in Madrid, Spain (9–13 September).
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