Researchers led by Nottingham Trent University have found you can speed up the metabolism
Removing a single gene from fat tissue can trick the body into burning more calories without the need for regular dieting, research shows. PHD2 is a gene that plays a key role regulating brown fat – a type of tissue that keeps a person warm in cold temperatures.
Dr Zoi Michailidou, a researcher in NTU ’s School of Science and Technology, said the findings could pave the way for new ways to treat obesity, type 2 diabetes and other diseases associated with being overweight. She said reducing the gene’s effect “may break the link between being overweight and type 2 diabetes, meaning our findings could be important for people with an increased risk of this disease”.
So the team wanted to find out if they could mimic this high-altitude effect by removing the PHD2 gene, which acts what the researchers describe as “an oxygen sensor for the body”, from brown fat tissue. The team also discovered the gene was associated with an increased risk of metabolic diseases such as diabetes and thyroid disorders.
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