The most effective medicine for migraines has been revealed in a comprehensive analysis by Oxford University researchers - with paracetamol proving surprisingly effective.
Some new migraine drugs are no more effective than paracetamol for treating attacks, a major study found.
But the Migraine Trust said it was often ‘a painful trial and error’ to find what works for individuals and urged doctors not to discount other medications. A new range of medicines including ubrogepant, atogepant and Rimegepant or ‘gepants’ were also tested, which bind to a protein released by the nerves at the start of a migraine attack.All were compared to the likes of paracetamol and anti-inflammatory painkillers for pain relief during an attack.
‘These drugs are four triptans; eletriptan, rizatriptan, sumatriptan and zolmitriptan. They are more efficacious than the other drugs and also they are better than the most recently marketed and more expensive drugs.’
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